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Home > Medicinal Mushrooms > Turkey Tail Extract | Standardized 40% Polysaccharide Content

Wild Harvested Turkey Tail (Trametes versicolor) Extract

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Turkey Tail Extract | 65 Grams
   
 
Turkey Tail (Trametes versicolor) Mycota

Turkey Tail (Trametes versicolor) mycota, or mushrooms/fungi, are one of the top medicinal fungi in the world, with extensive medical research backing its health promoting attributes. Clinical research in the US and Internationally have validated the unique ability of Turkey Tail mushrooms to attract and kill cancer cells. In addition, Turkey Tail is a potent immune modulator, increasing the production of T helper cells, those cells which direct the immune system. Today, cancer and immune system diseases seem to affect everyone at some point in their lives, using Turkey Tail not only helps to clean up mutated cells, but also repairs and strengthens the immune system through building T helper cell numbers. Turkey Tail has been the subject of 600 studies and 24 human clinical trials.

Turkey Tail mycota are one of the most thoroughly researched and respected of all the known medicinal mushrooms and fungi. Turkey Tail are medically significant for many reasons but they are most popularly known as being the natural source of the anti-cancer polysaccharide PSK. PSK (polysaccharide K) is a high molecular weight carbohydrate found in fruit and, in higher concentrations, in the mycelium of Turkey Tail. Our RAW Forest Foods' extract is a standardized extract, containing a potent 60% polysaccharide content.

One of the most common fungi to be found in the woods is Trametes versicolor, the turkey tail fungus. The common name come from the banding pattern on the fruiting bodies that resembles (in miniature, of course) the tail of a strutting turkey. The colors of the bands can be quite variable, depending on the genetics of the organism and its environment. Most of the bands are dark to light brown in color, alternating with light colored bands of white to tan, with still more bands of blue, orange, maroon, and other. The can be strikingly beautiful, and are among the most easily found fungi. The species has a widespread distribution, having been found in nearly every state in the United states and in most other countries.


Historical Use

Historically, the Turkey Tail fungus was referred to as Yun zhi in China. The first mention of Yun zhi was in the Bencao Gangmu (a.k.a. Compendium of Materia Medica), written by Li Shizhen during the Ming Dynasty (1578 CE). The Bencao Gangmu states that Turkey Tail, Yun zhi, "are beneficial to one's spirit and vital energy and strengthen one's tendon and bone."

Today, in Traditional Chinese Medicine (TCM), Turkey Tail is used to used to clear dampness, reduce phlegm, heal pulmonary disorders, strengthen the physique, increase energy and benefit people with chronic diseases (Yang &
Yong, 1989, Ying et al., 1987). Furthermore, Turkey Tail is employed by TCM doctors as a useful treatment for infection and/or inflammation of the upper respiratory, urinary and digestive tracts. Turkey Tail is also regarded as curative to liver ailments (including hepatitis B and chronic active hepatitis) and is used to treat general weakness of the immune system (Ying et al., 1987).

Active Medicinal Constituents

The largest US clinical trial on Turkey Tail was preformed by Bastyr University, which confirmed the use of Turkey Tail mushrooms in the treatment of several kinds of cancer, including cervical, breast, lung, gastric, colon, sarcoma, carcinoma, esophageal. The same study confirmed the use of Turkey Tail in cases of immunodeficiency, Hepatitis B and C, and Malaria.

Bastyr University isolated the following active medicinal constituents (compounds) in Turkey Tail.

  • β-glucan-proteins (Coriolan, PSK): anti-tumor, antiviral, immunomodulating. Polysaccharide K (PSK) is composed of 30% polysaccharide, 6% nitrogen, and 15% protein.
  • Ergosterol (pro-vitamin D2) derivatives: antitumor
  • Polysaccharopeptide (PSP): antiviral

RAW Forest Foods' Turkey Tail extract is a standardized extraction, with a 60% polysaccharide content, including the powerful PSK and PSP polysaccharides, which are responsible for the healing actions of the Turkey Tail fungus. The active medicinal constituents are identified as being anti-tumor, anti-microbial, immunomodulating, anti-oxidant, and anti-malaria.

Further Research Findings

The active polysaccharide PSK in Turkey Tail has documented anticancer activity in vitro (in human) clinical trials. Research has also demonstrated that the PSK polysaccharide can reduce mutagen-induced, radiation-induced, and spontaneously-induced cancer development. This is of particular interest to healthy, "cancer-free" people, as the environment is becoming more and more polluted with radiation (from nuclear power leaks, smart meters, cell phones, et cetera) , mutagens, and other cancer causing factors.

"The thermography shows the inflammation and degeneration caused by cell phone radiation. Notice the white areas from the ear down the throat to the lungs indicating degeneration and the red areas indicating inflammation - all caused by cellular radiation."

PSK has shown to be beneficial as an adjuvant in the treatment of gastric, esophageal, colorectal, breast, and lung cancers. Human clinical trials suggest PSK can reduce cancer recurrence when used as an adjuvant therapy. Research has demonstrated the mushroom can inhibit certain human cancer cell lines in vitro. Further in vitro studies have shown that a PSK in Turkey Tail can also inhibit cancer cell proliferation.

The United States’ top ranked cancer hospital MD Anderson has reported that Turkey Tail is a “promising candidate for chemo-prevention due to the multiple effects on the malignant process, limited side effects and safety of daily oral doses for extended periods of time. Turkey Tail is one of the mushrooms known in Eastern traditions as the "mushroom of immortality" and a "medicine of kings." known to boost the immune system, fight cancer, prevent heart disease, calm the nervous system, and relieve allergies and inflammation.



References

  1. cancer.org/docroot/ETO/content/ETO_5_3X_Coriolous_Versicolor.asp
  2. Chandler, Peter J. (2001), Fauna Entomologica Scandinavica, Leiden: Brill, pp. 1–278, ISBN 90-04-12023-8
  3. Oba K, Teramukai S, Kobayashi M, Matsui T, Kodera Y, Sakamoto J (June 2007), “Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curative resections of gastric cancer”, Cancer Immunol. Immunother. PMID 17106715.
  4. PMID 7606203
  5. Fisher, M; Yang, Lx (May 2002). “Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy”. Anticancer research ISSN 0250-7005. PMID 12168863.
  6. Sugimachi K, Maehara Y, Ogawa M, Kakegawa T, Tomita M (4 August 1997), “Dose intensity for patients with poorly differentiated gastric cancer”, Cancer Chemother Pharmacol (3): 233–8, doi:10.1007/s002800050652, PMID 9219507
  7. Hsieh TC, Wu JM (January 2001), “Cell growth and gene modulatory activities of Yunzhi (Windsor Wunxi) from mushroom Trametes versicolor in androgen-dependent and androgen-insensitive human prostate cancer cells”, Int J Oncol 81–8 PMID
  8. Dong Y, Yang MM, Kwan CY (1 January 1997), “In vitro inhibition of proliferation of HL-60 cells by trametes versicolor peptide PSK derived from Chinese medicinal herbs”, Life Sci 60 (8): 135–40, doi:10.1016/S0024-3205(96)00695-9, PMID 9042394
  9. Yang MM, Chen Z, Kwok JS (1 January 1992), “The anti-tumor effect of a small polypeptide from trametes versicolor (SPCV)”, Am J Chin Med PMID 1471606
  10. Clark D, Adams M (2009), “A commercial nutraceutical mix Metabolic Cell-Support (MC-S) inhibits proliferation of cancer cell lines in vitro”, Austr. J. Med. Herbal. 39–43
  11. Best Hospitals: Cancer, U.S. News and World Report, 12 July 2009
  12. Complementary/Integrative Medicine Education Resources. MD Anderson Cancer Center. www.mdanderson.org.
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