Paper Title: The Immune Modulating Properties of Pine Pollen.
Objective
Researchers Zhang Tun and Jianping Zhu conducted an observational study to determine the impact of Pine Pollen on positively modulating the immune system.
Study Methodology and Design
Randomly group the mice into four categories: negative control group (purified water), low-dosage, medium-dosage and high-dosage groups. Each group will be fed 0.25g, 0.5g and 1.5g/kg (body weight) with cell-broken Pine Pollen powder, which is equivalent to 5 times, 10 times, and 30 times of human clinical dosage.
After 30 days, we will conduct the following tests: serum hemolysin measurement, mice peritoneal macrophages phagocytosis ability test on chicken erythrocyte, dinitrofluorobenzene-induced delayed type hypersensitivity test (DTH), NK cell activity test, mice antibody formation (Hemolytic plaque number), thymus index, and spleen index test.
Influence of Pine Pollen on the Immune Modulation Function in Mice |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | Antibody Titre Level | Phagocytic Rate (%) | Phagocytic Index | Swelling Level (mg) | NK Cell Activity (%) | Thymus Index (%) | Spleen Index (%) | Hemolytic Plaque Number (*1000/Total Splenectomy) | OD Value + Control A | OD Value w/o Control A | Difference Value |
| Negative Control Group | 66.0 ± 18.5 | 11 ± 2.0 | 0.17 ± 0.03 | 19.6 ± 3.1 | 27.4 ± 3.9 | 0.26 ± 0.04 | 0.64 ± 0.07 | 9.7 ± 2.2 | 1.388 ± 0.027 | 1.304 ± 0.020 | 0.084 ± 0.009 |
| Low Dosage Group | 68.6 ± 24.2 | 11 ± 1.6 | 0.17 ± 0.03 | 17.6 ± 5.4 | 29.7+4.8 | 0.27 ± 0.05 | 0.66 ± 0.13 | 9.7 ± 2.9 | 1.405 ± 0.033 | 1.314 ± 0.023 | 0.091 ± 0.014 |
| Medium Dosage Group | 101.2 ± 25.1 (a) | 14+1.9 (a) | 0.23 ± 0.04 (a) | 22.4+3.5 | 33.0 ± 49 (a) | 0.26 ± 0.04 | 0.68 ± 0.16 | 14.4 ± 2.2 (a) | 1.433 ± 0.032 (a) | 1.312 ± 0.020 | 0.121 ± 0.015 (a) |
The levels of antibody titre, phagocytic rate, phagocytic index, swelling, hemolytic plaque numbers, NK cell activity, and the difference in ear size between the left and right ears due to dinitrofluorobenzene-induced delayed type hypersensitivity, were significantly higher in the medium and high dosage groups compared to the negative control group. However, there was no significant change in the Thymus index or Spleen index.
Conclusion and Significance
The experiment above demonstrates that cracked cell wall Pine Pollen can increase cellular immune function and cytophagy function. This increase might be due to the nutrition found in Pine Pollen.
Disclosures
Disclosures
Before making any changes to your diet or health regimen, including the use of dietary or nutritional supplements, we strongly recommend consulting with a healthcare practitioner. This advice is particularly relevant if you are pregnant, nursing, under the age of 18, have any known allergies, or have any pre-existing medical conditions.
At RAW Forest Foods, we are committed to your health and well-being. It is important to understand that our products are dietary supplements, not pharmaceuticals. We endeavor to provide high-quality supplements, but please be aware:
* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Ingredient Transparency and Allergen Awareness
Your safety and health are paramount. We strive to provide detailed ingredient information for each of our products to help you make informed choices. It is crucial not to consume any product containing ingredients to which you have, or suspect you may have, an allergy. Allergic reactions can be severe and, in some cases, life-threatening.
Interaction with Medications
If you are currently taking any medications, it is crucial to discuss potential interactions with your healthcare provider. Dietary supplements can interact with medications, potentially altering their effectiveness or leading to adverse effects.
Consult our full Terms and Conditions for additional information.