Twelve Rivers MycoMedic Tincture — Master Formulated Mushroom Complex — Bio-Available Dual Extract — 4 Ounces

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Primary Ingredients: Chaga, Cordyceps, Fu Shen, Maitake, Reishi, Royal Sun Agaricus, Turkey Tail, Willow Bracket
Features: Dual-Extracted using Whole Mushrooms, Gluten Free, Made in the USA, Ready to Use, UV Protected, Vegan
Tincture Volume: 4 Ounces
Servings per Container: 39
Product Guides: Female Friendly, Immune Tonics, Regenerative Nutrition, Tonics & Adaptogens
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Twelve Rivers MycoMedic Mushroom Formula

Discover the Wisdom of the Forest with Deep Immune Support

  • Our popular Twelve Rivers MycoMedic Mushroom Formula in a newly developed tincture;
  • 8 powerful medicinal mushrooms master formulated by our in-house herbalists, providing unparalleled immune support;
  • Full specific mushroom benefits: Adaptogenic, immunity, and tonic;
  • Made using only full, fruiting body mushrooms so you receive the strongest effects and benefits;
  • Unique dual extraction captures healing Beta-glucans, Polysaccharides, and Terpenes;
  • Alcohol suspension allows quick and efficient uptake;
  • Quality assured: Domestically produced in a certified organic, FDA cGMP facility.*

Twelve Rivers MycoMedic is ideal for daily use as an adaptogenic tonic and for supporting immune system health. As part of your herbal first aid kit, take Twelve Rivers MycoMedic at 2x the recommended dosage at the first sign of illness.

Twelve Rivers MycoMedic draws is inspired by the twelve energy Qi meridians in the body. Through acupuncture, Tai Chi and Qi Gong, and herbalism, health and wellness can be restored and enhanced by balancing these twelve meridians. Just like its namesake, Twelve Rivers is formulated to restore and enhance health and wellness by harnessing the power of medicinal mushrooms—in a complex, master developed formula.

To do this, Twelve Rivers MycoMedic formulates eight different medicinal mushrooms, all of which have well known health benefits. Harnessing each of the individual mushrooms, the single ingredients are synergized and amplified, not just combining their benefits but creating new additional advantages.

The Twelve Rivers formula is carefully and professionally crafted to provide fast, yet long-lasting benefits. Twelve Rivers is adaptogenic and tonic, meaning that it works with the body to holistically improve health and wellness.

As an immune system tonic, Twelve Rivers optimizes immune function—not simply stimulating. The ingredients in the formula have been shown to modulate the immune system, correcting both weak and overactive immune function (as seen with autoimmune disorders).*  Twelve Rivers MycoMedic is an immune system potentiator.

Because of the complex formula, this is the ideal product for anyone interested in gaining the benefits of medicine mushrooms.

Real Customer Reviews of our Twelve Rivers MycoMedic Formula

"Love the flavor, rich and delicious... HEALTHY most of all!" — Blanche-Marie

Twelve Rivers MycoMedic TinctureMade With Organic and Wild-Harvest Whole Fruiting Body Mushrooms

Mushrooms can be broken down into being composed of two parts: The fruiting body (the part of the mushrooms which you can see) and the mycelium (microscopic underground network). Of the two, the fruiting body contains the highest levels of beneficial compounds. It is, quite literally, the fruit of the organism.

Because the fruiting body contains the highest concentration on benefits, we craft this tincturing using only choice, whole fruiting body mushrooms:

  • Chaga (Inonotus obliquus);
  • Cordyceps (Cordyceps militaris);
  • Fu Shen (Poria cocos);
  • Maitake (Grifola frondosa; Hen-of-the-Woods);
  • Reishi (Ganoderma lucidum);
  • Royal Sun Agaricus (Agaricus blazei murill);
  • Turkey Tail (Trametes versicolor);
  • Willow Bracket (Phellinus igniarius).

Capturing the Trifecta: Beta-Glucans, Polysaccharides, and Terpenes

The major compounds responsible for the benefits of medicinal mushrooms are:

  • Beta-Glucans;
  • Polysaccharides;
  • Terpenes.

Most companies simply focus on the polysaccharides. While an important class of compounds, beta-glucans and terpenes are of—at least—equal importance. To offer you the most comprehensive product possible, this tincture undergoes two extracts (most tinctures only undergo one extraction). It is through this second stage extraction that we are able to capture the full potential of the ingredients and the formula—The trifecta of Beta-Glucans, Polysaccharides, and Terpenes. 

Twelve Rivers May Support

  • Peaceful and relaxed mental state;
  • Deeper, more restful sleep;
  • Immune system and improved resistance to disease;
  • Supports the entire body;
  • Assisting with energy and vitality;
  • Stress management;
  • Mental and spiritual well-being.*

Twelve Rivers Key Benefits

Adaptogenic and Tonic: Promoting Holistic, Full Body Support and Endocrine Health

Cordyceps (Cordyceps militaris), Reishi (Ganoderma lucidum), Fu Ling (Poria cocos), and Willow Bracket (Phellinus igniarius) are well known adaptogens used for millennia in Classical Chinese Medicine and Traditional Chinese Medicine, as well as by the indigenous North Americans. They have been used as tonics to fortify and strengthen the body, to relieve fatigue, and to reduce levels of stress, as well as to enhance the immune system and provide protection against diseases.

Deep Immune Support: Modulating and Potentiating the Immune System

Turkey Tail (Trametes versicolor), Maitake (Grifola frondosa), Royal Sun Agaricus (Agaricus blazei Murill), and Chaga (Inonotus obliquus) have also been used historically and traditionally by many cultures, and their effects have been recently proven through scientific research and academia. They have the ability to repair and recover the immune system, acting in many cases as immune system modulators. Research indicated these mushrooms may be useful in the prevention of cancer and tumors as adjunct therapy when used alongside allopathic cancer treatments like chemotherapy.* While the research is promising, we are in so way suggesting any mushroom or herb as a treatment—or preventative—for cancer.

Twelve Rivers Ingredient Sourcing

  • Chaga: Wild-harvested, Canadian;
  • Cordyceps: Cultivated, Organic, Domestic/US;
  • Fu Shen: Cultivated, Organic, Asia;
  • Maitake: Wild-harvested, Asia;
  • Reishi: Cultivated, Organic, Asia;
  • Royal Sun Agaricus: Cultivated, Organic, Domestic/US;
  • Turkey Tail: Cultivated, Organic, Domestic/US;
  • Willow Bracket: Wild-harvested, Asia.

Where to Buy Twelve Rivers MycoMedic Tincture?

RAW Forest Foods offers 2 and 4 ounce bottles of Twelve Rivers MycoMedic Tincture, with 19.5 servings in each 2 ounce bottle and 39 servings in each 4 ounce bottle. As with all of our products, we source our ingredients as close to the producers—farms and forests—as possible, visiting sites and meeting with growers, wild-harvesters, and processors.

RAW Forest Foods' Twelve Rivers MycoMedic Tincture have been lab-tested and verified for identity and microbial contamination (see below for the certificate of analysis on this product).

Further Availability

Twelve Rivers MycoMedic Tincture is available in 2 ounce and 4 ounce (this product) bottles, and as an Extract Powder. Additionally, the ingredients from Twelve Rivers MycoMedic are present in following:

Twelve Rivers MycoMedic Tincture

Twelve Rivers MycoMedic Tincture 4 Ounce Supplement Facts


To assist in supplementing and supporting immune function and the endocrine system, thereby promoting holistic, full-body health, wellness, vitality, and optimized aging. *

Suggested Usage

As a dietary supplement, adults take 3 mL (Approximately 3 dropperfuls) daily, preferably on an empty stomach. As with all dietary supplements, please consult a qualified healthcare practitioner prior to use.

For advanced support, increase to 2x daily. 

How to Take Twelve Rivers MycoMedic Tincture

Our favorite way to consume this product is with several ounces of water, taken on an empty stomach.

Learn more about using all of our products here.

CAUTION: do not exceed recommended dose.

Not for use by those under the age of 18, who are pregnant or nursing, or who are allergic or averse to any of the ingredients contained within.

How to Use Tonic and Adaptogenic Herbs

Twelve Rivers MycoMedic is an adaptogenic and tonic formula, and so being, consistency and time are vital in receiving the full benefits of it.

Adaptogens and tonics are herbs (in this case, mushrooms) which work with the body to to produce change and adaptation. In fact, the root word in “adaptogen” is adapt. This type of change—this type of adaptation—requires dedication, consistency, and time, but it is also the most profound and the most beneficial.

Before evaluating the effectiveness of any adaptogen or tonic, we advocate a trial of between four and six weeks of daily use.

Similar to exercise, while a single workout is good for you and will most like make you feel better, no real change will be seen without dedication, consistency, and time.

RAW Forest Foods offers a full 60 days refund policy on all products. This extended refund policy allows ample time for a customer to judge the effectiveness of these types of products.

And as the saying goes, “Give yourself enough time to be successful.” And give our Twelve Rivers MycoMedic enough time to be successful, too.

Ideal Storage

Keep out of the reach of children. Do not use if safety seal is damaged or missing. Store at room temperature.

Cycling Herbs

Herb cycling schedules can be beneficial when healing. If you prefer to rotate your adaptogenic, pro-androgenic, and tonic herbs, we suggest a schedule of five days on, and two days off, or four weeks on and one week off. *

Twelve Rivers MycoMedic Tincture Certificate of Analysis (CofA)


Before beginning this or any new medicinal herbs and nutritional supplements (from our company or elsewhere) customers are advised to consult with their qualified healthcare practitioner. We make this advice not because we question the safety of our products, but because we understand both in the strength of our products and that plants have medicinal, therapeutic potential.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

For more information, consult our full Terms and Conditions.

Quick Facts

View our Twelve Rivers MycoMedic Extract Powder quick facts PDF (Tincture PDF coming soon).

Works Referenced

Antitumor and anti-inflammatory activities of polysaccharides isolated from Ganoderma lucidum;
Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance;
Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms;
Clinical characteristics of gynecologic cancer patients who respond to salvage treatment with Lingzhi;
Ganoderma – a therapeutic fungal biofactory;
Ganoderma lucidum (Reishi) in cancer treatment;
Ganoderma lucidum exerts anti-tumor effects on ovarian cancer cells;
Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell;
Ganoderma lucidum stimulates NK cell cytotoxicity;
Ganoderma lucidum: a potent pharmacological macrofungus;
Immuno-modulatory activity of Ganoderma lucidum-derived polysacharide on human monocytoid dendritic cells pulsed with Der p 1 allergen;
Inhibitive effect on apoptosis in splenic lymphocytes of mice pretreated with lingzhi (Ganoderma lucidum) spores;
Natural products of the medicinal fungus Ganoderma lucidum: Occurrence, biological activities, and pharmacological functions;
Novel Antioxidant Peptides from Fermented Mushroom Ganoderma lucidum;
Randomized clinical trial of an ethanol extract of Ganoderma lucidum in men with lower urinary tract symptoms;
Reishi (Lingzhi), Wikipedia;
Reishi Mushroom (WebMD) uses, interactions, side effects and doseage;
Reishi mushroom cited effects;
Structural and immunological studies of a major polysaccharide from spores of Ganoderma lucidum (Fr.) Karst;
A comparative study of analytical methods for alkali-soluble β-glucan in medicinal mushroom, Chaga (Inonotus obliquus);
Chaga – The Facts;
Chaga mushroom (Inonotus obliquus) induces G0/G1 arrest and apoptosis in human hepatoma HepG2 cells;
Chaga Mushroom (Memorial Sloan Kettering Cancer Center);
Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis;
Inhibitory and Acceleratory Effects of Inonotus obliquus on Tyrosinase Activity and Melanin Formation in B16 Melanoma Cells;
Inonotus obliquus derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9;
Inonotus obliquus (Wikipedia);
King Chaga: Ruler Of The Land;
Oxidative stress response of Inonotus obliquus induced by hydrogen peroxide;
Prevention of Inonotus obliquus polysaccharides for high power microwave radiation induced testicular injury in rats: an experimental research;
Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells;
Stimulated production of steroids in Inonotus obliquus by host factors from birch;
The Healing Powers of Wild Chaga, Price-Pottenger Journal;
The History of Chaga in Herbal Medicine.

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